Rome2Rio

Prague to Madrid buses

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Trip Overview

The bus between Prague and Madrid takes 2d. The bus runs, on average, 2 times per week from Prague to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
2,438 km
Distance
€219
Average price
Twice a week
Frequency

Prague to Madrid bus times

Buses run twice a week between Prague and Madrid. The service departs Prague at 11:00 PM at night, which arrives into Madrid at 23:47:43. All services require a transfer at Strasbourg - L'Étoile Park Bus Station and take an average of 2d. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    RegioJetBlaBlaCar BusEmpresa Municipal de Transportes2d • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    RegioJetBlaBlaCar BusEmpresa Municipal de Transportes2d • 2 changes

Frequently asked questions

Want to know about travelling from Prague to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Madrid.ExpandLaunch map view
  • Distance: 2,438.3 km
  • Duration: 2d

What companies run services between Prague, Czechia and Madrid, Spain?

You can take a bus from Prague Florenc Central Bus Station to Neptuno via Strasbourg - L'Étoile Park Bus Station, Madrid, Estación Sur De Autobuses, and Méndez Álvaro - Terminal in around 33h 51m.

Operators