Prague to Nové Mesto bus times
Buses run every 4 hours between Prague and Nové Mesto. The earliest departure is at 1:45 AM at night, and the last departure from Prague is at 6:05 PM which arrives into Nové Mesto at 11:53 PM. All services require a transfer, and take on average 5h. The schedules shown below are for the next available departures.
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4h 34m • 1 change
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5h 4m • 1 change
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4h 39m • 1 change
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4h 59m • 1 change
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Departing Sunday, August 16, 2026
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4h 34m • 1 change
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4h 59m • 1 change
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4h 39m • 1 change
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4h 59m • 1 change
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Departing Monday, August 17, 2026
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4h 34m • 1 change
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4h 59m • 1 change
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4h 39m • 1 change
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4h 59m • 1 change
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Departing Tuesday, August 18, 2026
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4h 34m • 1 change
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4h 59m • 1 change
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4h 39m • 1 change
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4h 39m • 1 change
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Departing Wednesday, August 19, 2026
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4h 34m • 1 change
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4h 59m • 1 change
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4h 39m • 1 change
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4h 59m • 1 change
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Departing Thursday, August 20, 2026
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4h 34m • 1 change
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4h 59m • 1 change
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4h 39m • 1 change
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4h 59m • 1 change
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