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Prague to Southampton buses

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Trip Overview

The average bus between Prague and Southampton takes 26h 40m and the fastest bus takes 26h 20m. The bus runs, on average, 6 times per week from Prague to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 40m
Duration
895 mi
Distance
£130
Average price
6 times a week
Frequency

Prague to Southampton bus times

Buses run 6 times a week between Prague and Southampton. The earliest departure is at 9:45 AM in the morning, and the last departure from Prague is at 11:00 AM which arrives into Southampton at 1:00 PM. All services require a transfer, and take on average 26h 40m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    FlixBusNational Express27h • 1 change

Departing Thursday, November 5, 2026

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    Arrives next day

    FlixBusNational Express26h 20m • 1 change

Departing Friday, November 6, 2026

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    Arrives next day

    FlixBusNational Express26h 20m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    FlixBusNational Express26h 50m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    FlixBusNational Express26h 35m • 1 change

Frequently asked questions

Want to know about travelling from Prague to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Southampton.ExpandLaunch map view
  • Distance: 894.9 mi
  • Duration: 26h 40m

What companies run services between Prague, Czechia and Southampton, England?

You can take a bus from Praha, ÚAN Florenc to Coach Station via London Victoria in around 26h 58m.

Operators