Rome2Rio

Prague to Vatican Museums buses

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Trip Overview

The bus between Prague and Vatican Museums takes 21h 5m. The bus runs, on average, once a week from Prague to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 5m
Duration
1,432 km
Distance
€117
Average price
Once a week
Frequency

Prague to Vatican Museums bus times

Buses run once a week between Prague and Vatican Museums. The service departs Prague at 6:30 PM in the evening, which arrives into Vatican Museums at 15:35:00. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 21h 5m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    RegioJetATAC S.p.A. Azienda per la mobilità21h 5m • 1 change

Frequently asked questions

Want to know about travelling from Prague to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Vatican Museums.ExpandLaunch map view
  • Distance: 1,432 km
  • Duration: 21h 5m

What companies run services between Prague, Czechia and Vatican Museums, Vatican City?

RegioJet operates a bus from Prague Florenc Central Bus Station to Rome Tiburtina Bus Station once a week. Tickets cost €90–150 and the journey takes 20h 15m.

Operators