The average bus between Prague and Zeuthen takes 5h 14m and the fastest bus takes 4h 44m. The bus service runs several times per day from Prague to Zeuthen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Prague and Zeuthen. The earliest departure is at 4:15 AM at night, and the last departure from Prague is at 11:40 PM which arrives into Zeuthen at 5:24 AM. All services require a transfer at Berlin Südkreuz and take an average of 5h 14m. The schedules shown below are for the next available departures.


4h 44m • 2 changes

5h 59m • 2 changes

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5h 22m • 2 changes

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4h 52m • 2 changes

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6h 7m • 2 changes

4h 59m • 2 changes

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4h 49m • 2 changes

5h 4m • 2 changes

5h 34m • 2 changes

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5h 4m • 2 changes

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5h 34m • 2 changes

4h 44m • 2 changes

4h 59m • 2 changes

4h 52m • 2 changes

4h 52m • 2 changesWant to know about travelling from Prague to Zeuthen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Zeuthen. However, there are services departing from Prague Florenc Central Bus Station and arriving at Berlin Südkreuz station via Berlin Südkreuz station. The journey, including transfers, takes approximately 5h 14m.
Prague to Zeuthen bus services, operated by RegioJet, depart from Prague Florenc Central Bus Station.
Prague to Zeuthen bus services, operated by RegioJet, arrive at Berlin Südkreuz station.
Book your Prague to Zeuthen bus tickets online with Omio.
The distance between Prague and Zeuthen is 257.6 km. The road distance is 314 km.
RegioJet operates a bus from Prague Florenc Central Bus Station to Berlin Südkreuz hourly. Tickets cost €21–35 and the journey takes 4h 15m.