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Praha hl.n. to Brno buses

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Trip Overview

The average bus between Praha hl.n. and Brno takes 2h 32m and the fastest bus takes 2h 25m. The bus service runs several times per day from Praha hl.n. to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 32m
Duration
206 km
Distance
Kč 550
Average price
Every 3 hours
Frequency

Praha hl.n. to Brno bus times

Buses run every 3 hours between Praha hl.n. and Brno. The earliest departure is at 1:45 AM at night, and the last departure from Praha hl.n. is at 11:25 PM which arrives into Brno at 1:55 AM. All services run direct with no transfers required, and take on average 2h 32m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    bus bus 2h 35m • Direct
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    bus bus 2h 40m • Direct
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    bus bus 2h 50m • Direct
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    bus bus 2h 35m • Direct

Departing Wednesday, November 11, 2026

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    bus bus 2h 25m • Direct
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    bus bus 2h 30m • Direct
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    bus bus 2h 30m • Direct
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    bus bus 2h 35m • Direct
  • Show more

Departing Thursday, November 12, 2026

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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 30m • Direct
  • Show more

Departing Friday, November 13, 2026

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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 30m • Direct
  • Show more

Departing Saturday, November 14, 2026

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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 30m • Direct
  • Show more

Departing Sunday, November 15, 2026

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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
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    bus bus 2h 30m • Direct
  • Show more

Departing Monday, November 16, 2026

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    bus bus 2h 25m • Direct
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    bus bus 2h 25m • Direct
  •  → 

    bus bus 2h 25m • Direct
  •  → 

    bus bus 2h 30m • Direct
  • Show more

Frequently asked questions

Want to know about travelling from Praha hl.n. to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Praha hl.n. to Brno.ExpandLaunch map view
  • Distance: 205.8 km
  • Duration: 2h 32m

What companies run services between Praha hl.n., Czechia and Brno, Czechia?

FlixBus operates a bus from Praha, Hlavní Nádraží to Brno every 4 hours. Tickets cost Kč 450–700 and the journey takes 2h 35m. České dráhy (ČD) also services this route 4 times a week.

Operators