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Presque Isle to Fort Myers buses

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Trip Overview

The bus between Presque Isle and Fort Myers takes 2d 2h. The bus runs, on average, once a week from Presque Isle to Fort Myers. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 2h
Duration
1,975 mi
Distance
$389
Average price
Once a week
Frequency

Presque Isle to Fort Myers bus times

Buses run once a week between Presque Isle and Fort Myers. The service departs Presque Isle at 7:25 AM in the morning, which arrives into Fort Myers at 10:20:00. All services require a transfer at Bangor, ME and take an average of 2d 2h. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Cyr Bus LineAmtrak ThruwayFlixbus USAFlixbus USAFlixbus USA2d 2h • 4 changes

Frequently asked questions

Want to know about travelling from Presque Isle to Fort Myers? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Presque Isle to Fort Myers.ExpandLaunch map view
  • Distance: 1,975.2 mi
  • Duration: 2d 2h

What companies run services between Presque Isle, ME, USA and Fort Myers, FL, USA?

You can take a bus from Presque Isle, Maine to Fort Myers Bus Stop via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, Newark Penn Station, and Orlando Bus Station in around 42h 3m.

Operators