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Presque Isle to Indiana buses

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Trip Overview

The average bus between Presque Isle and Indiana takes 39h 11m and the fastest bus takes 32h 35m. The bus runs, on average, 5 times per week from Presque Isle to Indiana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 11m
Duration
1,424 mi
Distance
$264
Average price
5 times a week
Frequency

Presque Isle to Indiana bus times

Buses run 5 times a week between Presque Isle and Indiana. The earliest departure is at 7:25 AM in the morning, and the last departure from Presque Isle is at 7:25 AM which arrives into Indiana at 3:00 AM. All services require a transfer at Bangor, ME and take an average of 39h 11m. The schedules shown below are for the next available departures.

Departing Sunday, October 11, 2026

  •  → 

    Arrives next day

    Cyr Bus LineAmtrak ThruwayFlixbus USAFlixbus USA32h 35m • 3 changes

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    Cyr Bus LineAmtrak ThruwayGreyhound USAFlixbus USA43h 35m • 3 changes

Departing Wednesday, October 14, 2026

  •  → 

    Arrives +2 days

    Cyr Bus LineAmtrak ThruwayGreyhound USAFlixbus USA43h 35m • 3 changes

Departing Thursday, October 15, 2026

  •  → 

    Arrives +2 days

    Cyr Bus LineAmtrak ThruwayGreyhound USAFlixbus USA43h 35m • 3 changes

Frequently asked questions

Want to know about travelling from Presque Isle to Indiana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Presque Isle to Indiana.ExpandLaunch map view
  • Distance: 1,423.8 mi
  • Duration: 39h 11m

What companies run services between Presque Isle, ME, USA and Indiana, USA?

You can take a bus from Presque Isle, Maine to Indianapolis via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and Newark Penn Station in around 31h 35m.

Operators