The average bus between Province of Rome (Region) and Pisa takes 6h 18m and the fastest bus takes 5h 38m. The bus service runs several times per day from Province of Rome (Region) to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Province of Rome (Region) and Pisa. The earliest departure is at 12:00 AM at night, and the last departure from Province of Rome (Region) is at 11:30 PM which arrives into Pisa at 6:20 AM. All services require a transfer at Ponte Mammolo and take an average of 6h 18m. The schedules shown below are for the next available departures.


6h 19m • 2 changes


6h 15m • 2 changes


6h 25m • 2 changes


5h 38m • 2 changes


6h 19m • 2 changes


6h 15m • 2 changes


6h 30m • 2 changes


5h 38m • 2 changes


6h 15m • 2 changes


6h 30m • 2 changes


5h 38m • 2 changes
Arrives next day


6h 39m • 2 changes
Want to know about travelling from Province of Rome (Region) to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Province of Rome (Region) to Pisa. However, there are services departing from Province of Rome (Region) station and arriving at Pisa station via Pisa. The journey, including transfers, takes approximately 6h 18m.
Province of Rome (Region) to Pisa bus services, operated by Cotral S.p.A., depart from Roma, Autostazione Tiburtina station.
Province of Rome (Region) to Pisa bus services, operated by Cotral S.p.A., arrive at Pisa station.
The distance between Province of Rome (Region) and Pisa is 267.5 km. The road distance is 380 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 3 times a day. Tickets cost €30–55 and the journey takes 5h 30m.