The average bus between Province of Rome (Region) and Pisa takes 7h 9m and the fastest bus takes 5h 26m. The bus service runs several times per day from Province of Rome (Region) to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Province of Rome (Region) and Pisa. The earliest departure is at 6:58 AM in the morning, and the last departure from Province of Rome (Region) is at 11:00 PM which arrives into Pisa at 6:40 AM. All services require a transfer at ROMA | Rebibbia and take an average of 7h 9m. The schedules shown below are for the next available departures.


6h 8m • 2 changes

5h 26m • 2 changesArrives next day


9h 44m • 2 changes

6h 8m • 2 changes

5h 26m • 2 changesArrives next day


9h 44m • 2 changes

6h 16m • 2 changes

6h 10m • 2 changes

5h 26m • 2 changesArrives next day


9h 44m • 2 changes

6h 16m • 2 changes

6h 10m • 2 changes

5h 26m • 2 changesArrives next day


9h 44m • 2 changesWant to know about travelling from Province of Rome (Region) to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Province of Rome (Region) to Pisa. However, there are services departing from Province of Rome (Region) station and arriving at Pisa station via Pisa. The journey, including transfers, takes approximately 7h 9m.
Province of Rome (Region) to Pisa bus services, operated by Cotral S.p.A., depart from Roma, Autostazione Tiburtina station.
Province of Rome (Region) to Pisa bus services, operated by Cotral S.p.A., arrive at Pisa station.
The distance between Province of Rome (Region) and Pisa is 267.5 km. The road distance is 351 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 3 times a day. Tickets cost €27–45 and the journey takes 4h 35m.