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Province of Rome (Region) to Siena buses

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Trip Overview

The average bus between Province of Rome (Region) and Siena takes 3h 49m and the fastest bus takes 3h 25m. The bus service runs several times per day from Province of Rome (Region) to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 49m
Duration
250 km
Distance
€29
Average price
Every 4 hours
Frequency

Bus

best
  1. Take the bus from Roma, Autostazione Tiburtina to Sienabus bus 1550 / ...
4h 9m
€18–41

Province of Rome (Region) to Siena bus times

Buses run every 4 hours between Province of Rome (Region) and Siena. The earliest departure is at 5:28 AM in the morning, and the last departure from Province of Rome (Region) is at 8:55 PM which arrives into Siena at 12:40 AM. All services require a transfer at ROMA | Rebibbia and take an average of 3h 49m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 44m • 2 changes

Departing Saturday, November 7, 2026

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 46m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 36m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus4h 37m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 2 changes
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Departing Sunday, November 8, 2026

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 45m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus4h • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 55m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus4h 10m • 2 changes
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Departing Monday, November 9, 2026

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 36m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 52m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus4h 10m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 37m • 2 changes
  • Show more

Departing Tuesday, November 10, 2026

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 36m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 45m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 41m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 25m • 2 changes
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Departing Wednesday, November 11, 2026

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 45m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 41m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 25m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 38m • 2 changes
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Departing Thursday, November 12, 2026

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 36m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 52m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus4h 10m • 2 changes

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    Cotral S.p.A.ATAC S.p.A. Azienda per la mobilitàFlixBus3h 37m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Province of Rome (Region) to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Province of Rome (Region) to Siena.ExpandLaunch map view
  • Distance: 250 km
  • Duration: 3h 49m

What companies run services between Province of Rome (Region), Lazio, Italy and Siena, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Siena hourly. Tickets cost €20–30 and the journey takes 2h 40m. AutoLinee Moretti also services this route 3 times a week.

Operators