The average bus between Prunedale and San Luis Obispo takes 5h 14m and the fastest bus takes 3h 30m. The bus service runs several times per day from Prunedale to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Prunedale and San Luis Obispo. The earliest departure is at 8:20 AM in the morning, and the last departure from Prunedale is at 7:25 PM which arrives into San Luis Obispo at 3:55 AM. All services require a transfer at Salinas Transit Center / Gate 1 and take an average of 5h 14m. The schedules shown below are for the next available departures.

3h 36m • 1 change

3h 30m • 1 change
Arrives next day

8h 30m • 1 change

3h 36m • 1 change

3h 30m • 1 change
Arrives next day

8h 30m • 1 change

3h 36m • 1 change

3h 30m • 1 change
Arrives next day

8h 30m • 1 change

3h 36m • 1 change

3h 30m • 1 change
Arrives next day

8h 30m • 1 change
Want to know about travelling from Prunedale to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prunedale to San Luis Obispo. However, there are services departing from Prunedale station and arriving at San Luis Obispo station via San Luis Obispo. The journey, including transfers, takes approximately 5h 14m.
Prunedale to San Luis Obispo bus services, operated by Monterey-Salinas Transit, depart from Salinas station.
Prunedale to San Luis Obispo bus services, operated by Monterey-Salinas Transit, arrive at San Luis Obispo station.
The distance between Prunedale and San Luis Obispo is 189.2 km. The road distance is 221 km.
Amtrak operates a bus from Salinas to San Luis Obispo 4 times a day. Tickets cost $40–65 and the journey takes 3h 10m.