Rome2Rio

Pueblo to Des Moines buses

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Trip Overview

The average bus between Pueblo and Des Moines takes 20h 33m and the fastest bus takes 18h 25m. There is at least one bus per day from Pueblo to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 33m
Duration
799 mi
Distance
$174
Average price
Once daily
Frequency

Pueblo to Des Moines bus times

Buses run once daily between Pueblo and Des Moines. The earliest departure is at 6:50 AM in the morning, and the last departure from Pueblo is at 1:30 PM which arrives into Des Moines at 8:55 AM. All services require a transfer, and take on average 20h 33m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Flixbus USAGreyhound USA18h 25m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Flixbus USAGreyhound USA18h 25m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA25h 5m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAGreyhound USA18h 25m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Flixbus USAGreyhound USA18h 25m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAGreyhound USA18h 25m • 1 change

Frequently asked questions

Want to know about travelling from Pueblo to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pueblo to Des Moines.ExpandLaunch map view
  • Distance: 799 mi
  • Duration: 20h 33m

What companies run services between Pueblo, CO, USA and Des Moines, IA, USA?

You can take a bus from Pueblo Transit to Des Moines via Denver Union Station in around 16h 25m.

Operators