Rome2Rio

Quality Hotel Nova Domus, Rome to Florence buses

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Trip Overview

The average bus between Quality Hotel Nova Domus, Rome and Florence takes 4h 28m and the fastest bus takes 3h 52m. There is a bus service every few hours from Quality Hotel Nova Domus, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 28m
Duration
286 km
Distance
€32
Average price
Hourly
Frequency

Quality Hotel Nova Domus, Rome to Florence bus times

Buses run hourly between Quality Hotel Nova Domus, Rome and Florence. The earliest departure is at 5:35 AM in the morning, and the last departure from Quality Hotel Nova Domus, Rome is at 9:58 PM which arrives into Florence at 2:10 AM. All services require a transfer at C.Ne Trionfale/Telesio and take an average of 4h 28m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 26m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 6m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 26m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 35m • 1 change
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Departing Saturday, November 14, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 39m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 12m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 28m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 33m • 1 change
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Departing Sunday, November 15, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 27m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 4m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 27m • 1 change
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Departing Monday, November 16, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 36m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 28m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 49m • 1 change
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Departing Tuesday, November 17, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 36m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 28m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 49m • 1 change
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Departing Wednesday, November 18, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 28m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 49m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 1 change
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Departing Thursday, November 19, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 36m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 17m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 28m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 49m • 1 change
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Frequently asked questions

Want to know about travelling from Quality Hotel Nova Domus, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Quality Hotel Nova Domus, Rome to Florence.ExpandLaunch map view
  • Distance: 286.2 km
  • Duration: 4h 28m

What companies run services between Quality Hotel Nova Domus, Rome, Italy and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators