Quality Hotel Nova Domus, Rome to Florence Buses

Quality Hotel Nova Domus, Rome to Florence buses

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Trip Overview

The average bus between Quality Hotel Nova Domus, Rome and Florence takes 4h 19m and the fastest bus takes 3h 52m. There is a bus service every few hours from Quality Hotel Nova Domus, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 19m
Duration: 286 km
Distance: €32
Average price: Hourly
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...

4h 30m

€16–48

Quality Hotel Nova Domus, Rome to Florence bus times

Buses run hourly between Quality Hotel Nova Domus, Rome and Florence. The earliest departure is at 5:49 AM in the morning, and the last departure from Quality Hotel Nova Domus, Rome is at 10:15 PM which arrives into Florence at 2:10 AM. All services require a transfer at C.Ne Trionfale/Telesio and take an average of 4h 19m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

7:13 AM → 11:10 AM
3h 56m • 1 change
7:40 AM → 11:45 AM
4h 4m • 1 change
8:02 AM → 12:30 PM
4h 27m • 1 change
8:46 AM → 12:45 PM
3h 58m • 1 change
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Departing Monday, November 2, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:30 PM
4h 33m • 1 change
Show more

Departing Tuesday, November 3, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:30 PM
4h 33m • 1 change
Show more

Departing Wednesday, November 4, 2026

7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:30 PM
4h 33m • 1 change
9:09 AM → 1:25 PM
4h 15m • 1 change
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Departing Thursday, November 5, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:30 PM
4h 33m • 1 change
Show more

Departing Friday, November 6, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:30 PM
4h 33m • 1 change
Show more

Departing Saturday, November 7, 2026

5:50 AM → 10:15 AM
4h 24m • 1 change
7:09 AM → 11:10 AM
4h • 1 change
7:39 AM → 11:45 AM
4h 5m • 1 change
8:09 AM → 12:30 PM
4h 20m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Quality Hotel Nova Domus, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.