Quality Hotel Nova Domus, Rome to Florence Buses

Quality Hotel Nova Domus, Rome to Florence buses

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Trip Overview

The average bus between Quality Hotel Nova Domus, Rome and Florence takes 4h 18m and the fastest bus takes 3h 50m. There is a bus service every few hours from Quality Hotel Nova Domus, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 18m
Duration: 286 km
Distance: €32
Average price: Hourly
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...

4h 30m

€16–44

Quality Hotel Nova Domus, Rome to Florence bus times

Buses run hourly between Quality Hotel Nova Domus, Rome and Florence. The earliest departure is at 5:48 AM in the morning, and the last departure from Quality Hotel Nova Domus, Rome is at 10:15 PM which arrives into Florence at 2:10 AM. All services require a transfer at C.Ne Trionfale/Telesio and take an average of 4h 18m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

4:49 PM → 9:15 PM
4h 25m • 1 change
6:18 PM → 10:30 PM
4h 11m • 1 change
6:31 PM → 11:20 PM
4h 48m • 1 change
8:02 PM → 12:50 AM
Arrives next day
4h 47m • 1 change
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Departing Saturday, October 24, 2026

5:50 AM → 10:15 AM
4h 24m • 1 change
7:09 AM → 11:10 AM
4h • 1 change
7:39 AM → 11:45 AM
4h 5m • 1 change
8:09 AM → 12:15 PM
4h 5m • 1 change
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Departing Sunday, October 25, 2026

5:48 AM → 10:15 AM
4h 26m • 1 change
6:46 AM → 10:45 AM
3h 58m • 1 change
7:15 AM → 11:10 AM
3h 54m • 1 change
8:04 AM → 12:15 PM
4h 10m • 1 change
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Departing Monday, October 26, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:15 PM
4h 18m • 1 change
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Departing Tuesday, October 27, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:15 PM
4h 18m • 1 change
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Departing Wednesday, October 28, 2026

7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:15 PM
4h 18m • 1 change
8:33 AM → 12:45 PM
4h 11m • 1 change
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Departing Thursday, October 29, 2026

5:49 AM → 10:15 AM
4h 25m • 1 change
7:05 AM → 11:10 AM
4h 4m • 1 change
7:20 AM → 11:45 AM
4h 24m • 1 change
7:56 AM → 12:15 PM
4h 18m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Quality Hotel Nova Domus, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.