The average bus between Reading and St. Louis takes 29h 15m and the fastest bus takes 24h 35m. The bus service runs several times per day from Reading to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Reading and St. Louis. The earliest departure is at 1:15 AM at night, and the last departure from Reading is at 3:35 PM which arrives into St. Louis at 3:10 PM. All services require a transfer, and take on average 29h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from Reading to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Reading to St. Louis. However, there are services departing from Reading station and arriving at St Louis Bus Station via Harrisburg Bus Station. The journey, including transfers, takes approximately 29h 15m.
Reading to St. Louis bus services, operated by Flixbus USA, depart from Reading station.
Reading to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Reading to St. Louis bus tickets online with Omio and FlixBus.
The distance between Reading and St. Louis is 1238 km. The road distance is 1347 km.
You can take a bus from Reading to St Louis Bus Station via Harrisburg Bus Station in around 21h.
