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Reading to St. Louis buses

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Trip Overview

The average bus between Reading and St. Louis takes 29h 49m and the fastest bus takes 24h 35m. There is at least one bus per day from Reading to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 49m
Duration
864 mi
Distance
$191
Average price
Once daily
Frequency

Reading to St. Louis bus times

Buses run once daily between Reading and St. Louis. The earliest departure is at 1:15 AM at night, and the last departure from Reading is at 3:35 PM which arrives into St. Louis at 3:10 PM. All services require a transfer, and take on average 29h 49m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA32h • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA32h • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA24h 35m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA24h 35m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA32h • 1 change
  •  → 

    Arrives next day

    Flixbus USAGreyhound USA24h 35m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA32h • 1 change

Frequently asked questions

Want to know about travelling from Reading to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Reading to St. Louis.ExpandLaunch map view
  • Distance: 863.7 mi
  • Duration: 29h 49m

What companies run services between Reading, PA, USA and St. Louis, MO, USA?

You can take a bus from Reading to St Louis Bus Station via Harrisburg Bus Station in around 21h.

Operators