The average bus between Regensburg and Mainz takes 8h 26m and the fastest bus takes 6h 5m. The bus service runs several times per day from Regensburg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Regensburg and Mainz. The earliest departure is at 4:20 AM at night, and the last departure from Regensburg is at 11:50 PM which arrives into Mainz at 8:15 AM. All services require a transfer, and take on average 8h 26m. The schedules shown below are for the next available departures.

6h 5m • 1 change

8h 50m • 1 change
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8h 25m • 1 change

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8h 25m • 1 change

6h 5m • 1 change

8h 50m • 1 change
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8h 25m • 1 change

6h 5m • 1 change

8h 50m • 1 change
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8h 25m • 1 change

6h 5m • 1 change

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8h 25m • 1 change
Want to know about travelling from Regensburg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Regensburg to Mainz. However, there are services departing from Regensburg station and arriving at Mainz station via Frankfurt central train station station. The journey, including transfers, takes approximately 8h 26m.
Regensburg to Mainz bus services, operated by FlixBus, depart from Regensburg central train station.
Regensburg to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Book your Regensburg to Mainz bus tickets online with FlixBus.
The distance between Regensburg and Mainz is 296.3 km. The road distance is 365 km.
FlixBus operates a bus from Regensburg central train station to Frankfurt central train station 5 times a day. Tickets cost €27–45 and the journey takes 4h 10m.