The average bus between Reno and Mission Viejo takes 18h 9m and the fastest bus takes 17h 35m. The bus service runs several times per day from Reno to Mission Viejo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Reno and Mission Viejo. The earliest departure is at 6:45 AM in the morning, and the last departure from Reno is at 10:35 AM which arrives into Mission Viejo at 5:20 AM. All services require a transfer at Sacramento Bus Station and take an average of 18h 9m. The schedules shown below are for the next available departures.
Arrives next day



17h 35m • 3 changes
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18h 45m • 3 changes
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17h 35m • 3 changes
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19h 15m • 3 changes
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17h 35m • 3 changes
Arrives next day



18h 45m • 3 changes
Want to know about travelling from Reno to Mission Viejo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Reno to Mission Viejo. However, there are services departing from Reno station and arriving at Mission Viejo station via Sacramento Bus Station station. The journey, including transfers, takes approximately 18h 9m.
Reno to Mission Viejo bus services, operated by Greyhound USA, depart from Reno Amtrak station.
Reno to Mission Viejo bus services, operated by Greyhound USA, arrive at Anaheim Regional Transportation Intermodal Center station.
The distance between Reno and Mission Viejo is 686.5 km. The road distance is 975 km.
You can take a bus from Reno Amtrak to Laguna Hills Trans Ctr Dock 6 via Sacramento Bus Station, Anaheim Regional Transportation Intermodal Center, Artic - Dock 5, and Katella-Harbor in around 16h 39m.