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Roanoke to Gainesville buses

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Trip Overview

The bus between Roanoke and Gainesville takes 2d 8h. The bus runs, on average, 2 times per week from Roanoke to Gainesville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 8h
Duration
875 mi
Distance
Twice a week
Frequency

Roanoke to Gainesville bus times

Buses run twice a week between Roanoke and Gainesville. The earliest departure is at 3:25 AM at night, and the last departure from Roanoke is at 4:25 AM which arrives into Gainesville at 11:59 AM. All services require a transfer at Charlottesville Union Station and take an average of 2d 8h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +2 days

    Greyhound USAAmtrakFlixbus USAFlixbus USA2d 8h • 3 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    Greyhound USAAmtrakFlixbus USAFlixbus USA2d 8h • 3 changes

Frequently asked questions

Want to know about travelling from Roanoke to Gainesville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roanoke to Gainesville.ExpandLaunch map view
  • Distance: 874.9 mi
  • Duration: 2d 8h

What companies run services between Roanoke, VA, USA and Gainesville, FL, USA?

You can take a bus from Roanoke Bus Stop to Gainesville via Charlottesville Union Station, Charlottesville Amtrak Station, Richmond, and Jacksonville in around 20h 54m.

Operators