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Roanoke to Mississippi buses

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Trip Overview

The bus between Roanoke and Mississippi takes 25h. The bus runs, on average, 6 times per week from Roanoke to Mississippi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h
Duration
856 mi
Distance
$183
Average price
6 times a week
Frequency

Roanoke to Mississippi bus times

Buses run 6 times a week between Roanoke and Mississippi. The service departs Roanoke at 12:45 PM in the afternoon, which arrives into Mississippi at 12:45:00. All services require a transfer at Nashville Bus Station and take an average of 25h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA25h • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA25h • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA25h • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA25h • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA25h • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA25h • 2 changes

Frequently asked questions

Want to know about travelling from Roanoke to Mississippi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roanoke to Mississippi.ExpandLaunch map view
  • Distance: 855.6 mi
  • Duration: 25h

What companies run services between Roanoke, VA, USA and Mississippi, USA?

You can take a bus from Roanoke Bus Stop to Jackson via Nashville Bus Station and Memphis Bus Station in around 17h 25m.

Operators