Rome2Rio

Rochester to La Crosse buses

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Trip Overview

The bus between Rochester and La Crosse takes 39h 25m. The bus runs, on average, 6 times per week from Rochester to La Crosse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 25m
Duration
910 mi
Distance
$217
Average price
6 times a week
Frequency

Rochester to La Crosse bus times

Buses run 6 times a week between Rochester and La Crosse. The service departs Rochester at 9:15 PM at night, which arrives into La Crosse at 12:40:00. All services require a transfer at Cleveland Bus Station and take an average of 39h 25m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines39h 25m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines39h 25m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines39h 25m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines39h 25m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAJefferson Lines39h 25m • 3 changes

Frequently asked questions

Want to know about travelling from Rochester to La Crosse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rochester to La Crosse.ExpandLaunch map view
  • Distance: 909.5 mi
  • Duration: 39h 25m

What companies run services between Rochester, NY, USA and La Crosse, WI, USA?

You can take a bus from Rochester Bus Stop to La Crosse via Cleveland Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 20h 50m.

Operators