The average bus between Rochester and West Seneca takes 2h 38m and the fastest bus takes 1h 56m. The bus service runs several times per day from Rochester to West Seneca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rochester and West Seneca. The earliest departure is at 2:30 AM at night, and the last departure from Rochester is at 7:55 PM which arrives into West Seneca at 10:41 PM. All services require a transfer at Buffalo and take an average of 2h 38m. The schedules shown below are for the next available departures.

3h 6m • 1 change

2h 4m • 1 change

1h 56m • 1 change

2h 46m • 1 change

3h 6m • 1 change

2h 4m • 1 change

1h 56m • 1 change

2h 46m • 1 change

3h 6m • 1 change

2h 4m • 1 change

1h 56m • 1 change

2h 46m • 1 change
Want to know about travelling from Rochester to West Seneca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rochester to West Seneca. However, there are services departing from Rochester station and arriving at West Seneca station via Buffalo. The journey, including transfers, takes approximately 2h 38m.
Rochester to West Seneca bus services, operated by Trailways, depart from Rochester station.
Rochester to West Seneca bus services, operated by Trailways, arrive at Seneca Street & Maywood Place station.
The distance between Rochester and West Seneca is 102.1 km. The road distance is 131 km.
You can take a bus from Rochester to Seneca Street & Maywood Place via Buffalo and Lower Terrace & Adams Mark in around 2h 19m.