Rome2Rio

Roma Termini to Brindisi buses

Find Transport to Brindisi

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Roma Termini and Brindisi takes 10h 11m and the fastest bus takes 8h 45m. The bus service runs several times per day from Roma Termini to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 11m
Duration
543 km
Distance
€56
Average price
Twice daily
Frequency

Roma Termini to Brindisi bus times

Buses run twice daily between Roma Termini and Brindisi. The earliest departure is at 6:45 AM in the morning, and the last departure from Roma Termini is at 4:20 PM which arrives into Brindisi at 6:10 AM. All services require a transfer at Termini and take an average of 10h 11m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 40m • 1 change
  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 14m • 1 change
  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change
  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus13h 50m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 40m • 1 change
  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 14m • 1 change
  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change
  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus13h 50m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Cotral S.p.A.FlixBus9h 54m • 1 change

Frequently asked questions

Want to know about travelling from Roma Termini to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roma Termini to Brindisi.ExpandLaunch map view
  • Distance: 543.3 km
  • Duration: 10h 11m

What companies run services between Roma Termini, Italy and Brindisi, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Brindisi 5 times a day. Tickets cost €45–75 and the journey takes 7h 25m.

Operators