The average bus between Roma Termini and Lecce takes 10h 15m and the fastest bus takes 8h. The bus service runs several times per day from Roma Termini to Lecce. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Roma Termini and Lecce. The earliest departure is at 5:35 AM in the morning, and the last departure from Roma Termini is at 4:20 PM which arrives into Lecce at 6:45 AM. All services require a transfer at Tiburtina F.s. and take an average of 10h 15m. The schedules shown below are for the next available departures.

9h 3m • 1 change

8h 45m • 1 change

9h 20m • 1 change

8h • 1 change
Want to know about travelling from Roma Termini to Lecce? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Roma Termini to Lecce. However, there are services departing from Roma Termini station and arriving at Lecce station via Lecce Central Bus Station station. The journey, including transfers, takes approximately 10h 15m.
Roma Termini to Lecce bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Rome Tiburtina Largo Mazzoni station.
Roma Termini to Lecce bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Lecce Central Bus Station.
Book your Roma Termini to Lecce bus tickets online with ATAC S.p.A. Azienda per la mobilità and FlixBus.
The distance between Roma Termini and Lecce is 505 km. The road distance is 592 km.
Itabus S.p.A. operates a bus from Rome Tiburtina Largo Mazzoni to Lecce Central Bus Station once daily. Tickets cost €35–70 and the journey takes 8h 25m.