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Roma Termini to Madrid buses

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Trip Overview

The average bus between Roma Termini and Madrid takes 37h 31m and the fastest bus takes 33h 45m. There is at least one bus per day from Roma Termini to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

37h 31m
Duration
2,023 km
Distance
€206
Average price
Once daily
Frequency

Roma Termini to Madrid bus times

Buses run once daily between Roma Termini and Madrid. The earliest departure is at 12:44 AM at night, and the last departure from Roma Termini is at 4:20 PM which arrives into Madrid at 9:30 AM. All services require a transfer at Termini and take an average of 37h 31m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes
  •  → 

    Arrives +2 days

    Cotral S.p.A.FlixBusFlixBus2d 3h • 2 changes

Departing Saturday, November 7, 2026

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    Arrives +2 days

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus42h 10m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBus33h 45m • 2 changes

Frequently asked questions

Want to know about travelling from Roma Termini to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roma Termini to Madrid.ExpandLaunch map view
  • Distance: 2,022.5 km
  • Duration: 37h 31m

What companies run services between Roma Termini, Italy and Madrid, Spain?

You can take a vehicle from Roma Termini to Madrid via Termini, Rome Tiburtina Bus station, and Genoa in around 29h 59m.

Operators