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Roma Termini to Prague buses

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Trip Overview

The average bus between Roma Termini and Prague takes 24h 32m and the fastest bus takes 20h 50m. The bus runs, on average, 3 times per week from Roma Termini to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 32m
Duration
1,430 km
Distance
Kč 2,625
Average price
3 times a week
Frequency

Roma Termini to Prague bus times

Buses run 3 times a week between Roma Termini and Prague. The earliest departure is at 6:45 AM in the morning, and the last departure from Roma Termini is at 12:20 PM which arrives into Prague at 9:10 AM. All services require a transfer at Termini and take an average of 24h 32m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    Cotral S.p.A.RegioJet26h 24m • 1 change

Departing Friday, November 6, 2026

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    Arrives next day

    Cotral S.p.A.RegioJet26h 24m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàRegioJet20h 50m • 1 change

Frequently asked questions

Want to know about travelling from Roma Termini to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roma Termini to Prague.ExpandLaunch map view
  • Distance: 1,429.9 km
  • Duration: 24h 32m

What companies run services between Roma Termini, Italy and Prague, Czechia?

RegioJet operates a bus from Rome Tiburtina Bus Station to Prague Florenc Central Bus Station 4 times a week. Tickets cost Kč 2,100–3,600 and the journey takes 20h 10m.

Operators