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Roma Termini to Siena Cathedral buses

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Trip Overview

The average bus between Roma Termini and Siena Cathedral takes 4h 2m and the fastest bus takes 3h 20m. The bus service runs several times per day from Roma Termini to Siena Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 2m
Duration
239 km
Distance
€22
Average price
3 times a day
Frequency

Roma Termini to Siena Cathedral bus times

Buses run 3 times a day between Roma Termini and Siena Cathedral. The earliest departure is at 5:36 AM in the morning, and the last departure from Roma Termini is at 4:20 PM which arrives into Siena Cathedral at 8:24 PM. All services require a transfer at Termini and take an average of 4h 2m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 35m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 20m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 20m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 35m • 1 change
  • Show more

Departing Monday, November 9, 2026

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    Cotral S.p.A.FlixBus3h 29m • 1 change
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    Cotral S.p.A.FlixBus3h 49m • 1 change

Departing Tuesday, November 10, 2026

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    Cotral S.p.A.FlixBus3h 29m • 1 change
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    Cotral S.p.A.FlixBus8h 14m • 1 change

Departing Wednesday, November 11, 2026

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    Cotral S.p.A.FlixBus8h 14m • 1 change

Departing Thursday, November 12, 2026

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    Cotral S.p.A.FlixBus3h 29m • 1 change
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    Cotral S.p.A.FlixBus3h 49m • 1 change

Departing Friday, November 13, 2026

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    Cotral S.p.A.FlixBus3h 29m • 1 change
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    Cotral S.p.A.FlixBus3h 49m • 1 change

Departing Saturday, November 14, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 38m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 35m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 20m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 20m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Roma Termini to Siena Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roma Termini to Siena Cathedral.ExpandLaunch map view
  • Distance: 238.7 km
  • Duration: 4h 2m

What companies run services between Roma Termini, Italy and Siena Cathedral, Tuscany, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Siena hourly. Tickets cost €20–35 and the journey takes 2h 40m. AutoLinee Moretti also services this route 3 times a week.

Operators