Rome2Rio

Roma Termini to Siena Station buses

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Trip Overview

The average bus between Roma Termini and Siena Station takes 4h 57m and the fastest bus takes 3h 50m. There is at least one bus per day from Roma Termini to Siena Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 57m
Duration
236 km
Distance
€22
Average price
Once daily
Frequency

Roma Termini to Siena Station bus times

Buses run once daily between Roma Termini and Siena Station. The earliest departure is at 6:45 AM in the morning, and the last departure from Roma Termini is at 8:20 AM which arrives into Siena Station at 11:10 AM. All services require a transfer at Termini and take an average of 4h 57m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Cotral S.p.A.FlixBus5h 24m • 1 change

Departing Thursday, November 12, 2026

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    Cotral S.p.A.FlixBus5h 24m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Cotral S.p.A.FlixBus5h 24m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 50m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 50m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Cotral S.p.A.FlixBus5h 24m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Cotral S.p.A.FlixBus5h 24m • 1 change

Frequently asked questions

Want to know about travelling from Roma Termini to Siena Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roma Termini to Siena Station.ExpandLaunch map view
  • Distance: 236.5 km
  • Duration: 4h 57m

What companies run services between Roma Termini, Italy and Siena Station, Italy?

Itabus S.p.A. operates a bus from Rome Tiburtina Largo Mazzoni to Siena Central Train Station 5 times a week. Tickets cost €11–21 and the journey takes 2h 50m. FlixBus also services this route twice daily.

Operators