Rome2Rio

Rome Termini to Brindisi buses

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Trip Overview

The average bus between Rome Termini and Brindisi takes 8h 18m and the fastest bus takes 7h 51m. The bus service runs several times per day from Rome Termini to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 18m
Duration
543 km
Distance
€64
Average price
5 times a day
Frequency

Bus

best
  1. Take the bus from Roma, Autostazione Tiburtina to Brindisibus bus 573 / ...
8h 51m
€46–78

Rome Termini to Brindisi bus times

Buses run 5 times a day between Rome Termini and Brindisi. The earliest departure is at 7:42 AM in the morning, and the last departure from Rome Termini is at 11:21 PM which arrives into Brindisi at 7:15 AM. All services require a transfer at Indipendenza and take an average of 8h 18m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 4m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 59m • 1 change

Departing Sunday, November 8, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 57m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 41m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 51m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 2m • 1 change
  • Show more

Departing Monday, November 9, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 47m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 57m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 2m • 1 change
  • Show more

Departing Tuesday, November 10, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 47m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 57m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 2m • 1 change
  • Show more

Departing Wednesday, November 11, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 47m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 57m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 2m • 1 change
  • Show more

Departing Thursday, November 12, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 47m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 57m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 2m • 1 change
  • Show more

Departing Friday, November 13, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change

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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 47m • 1 change

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus7h 57m • 1 change

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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 2m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Rome Termini to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome Termini to Brindisi.ExpandLaunch map view
  • Distance: 542.7 km
  • Duration: 8h 18m

What companies run services between Rome Termini, Italy and Brindisi, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Brindisi every 3 hours. Tickets cost €45–70 and the journey takes 7h 25m.

Operators