The average bus between Rome Termini and Siena Station takes 3h 14m and the fastest bus takes 3h 2m. The bus service runs several times per day from Rome Termini to Siena Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Rome Termini and Siena Station. The earliest departure is at 6:00 AM in the morning, and the last departure from Rome Termini is at 9:17 PM which arrives into Siena Station at 12:40 AM. All services require a transfer at Indipendenza and take an average of 3h 14m. The schedules shown below are for the next available departures.

3h 7m • 1 change

3h 7m • 1 change

3h 10m • 1 change
Arrives next day

3h 27m • 1 change

3h 13m • 1 change

3h 7m • 1 change

3h 13m • 1 change

3h 7m • 1 change

3h 2m • 1 change

3h 11m • 1 change

3h 17m • 1 change

3h 20m • 1 change

3h 2m • 1 change

3h 11m • 1 change

3h 17m • 1 change

3h 20m • 1 change

3h 14m • 1 change

3h 17m • 1 change

3h 17m • 1 change

3h 28m • 1 change

3h 14m • 1 change

3h 17m • 1 change

3h 17m • 1 change

3h 28m • 1 change
Want to know about travelling from Rome Termini to Siena Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome Termini to Siena Station. However, there are services departing from Rome Termini station and arriving at Siena Station station via Siena. The journey, including transfers, takes approximately 3h 14m.
Rome Termini to Siena Station bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Rome Termini to Siena Station bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Siena station.
The distance between Rome Termini and Siena Station is 185.8 km. The road distance is 236 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Siena every 3 hours. Tickets cost €19–35 and the journey takes 2h 39m. AutoLinee Moretti also services this route 3 times a week.