The average bus between Rome and Castel San Pietro Terme takes 6h 12m and the fastest bus takes 5h 45m. The bus service runs several times per day from Rome to Castel San Pietro Terme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rome and Castel San Pietro Terme. The earliest departure is at 12:40 AM at night, and the last departure from Rome is at 7:25 AM which arrives into Castel San Pietro Terme at 4:00 PM. All services require a transfer, and take on average 6h 12m. The schedules shown below are for the next available departures.

5h 50m • 1 change

5h 45m • 1 change

8h 30m • 1 change

8h 35m • 1 change

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5h 45m • 1 change

8h 30m • 1 change

8h 35m • 1 change

5h 50m • 1 change

5h 45m • 1 change

8h 30m • 1 change

8h 35m • 1 change

5h 50m • 1 change

5h 45m • 1 change

8h 30m • 1 change

8h 35m • 1 change
Want to know about travelling from Rome to Castel San Pietro Terme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Castel San Pietro Terme. However, there are services departing from Rome station and arriving at Castel San Pietro Terme station via Bologna Autostazione. The journey, including transfers, takes approximately 6h 12m.
Rome to Castel San Pietro Terme bus services, operated by FlixBus, depart from Rome Tiburtina Largo Mazzoni station.
Rome to Castel San Pietro Terme bus services, operated by FlixBus, arrive at Bologna Autostazione station.
The distance between Rome and Castel San Pietro Terme is 287.4 km. The road distance is 419 km.
Itabus S.p.A. operates a bus from Rome Tiburtina Largo Mazzoni to Bologna Autostazione every 4 hours. Tickets cost €24–50 and the journey takes 5h 15m. Two other operators also service this route.