Rome2Rio

Rome to Karlsruhe buses

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Trip Overview

The bus between Rome and Karlsruhe takes 18h 35m. There is at least one bus per day from Rome to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 35m
Duration
1,184 km
Distance
€130
Average price
Once daily
Frequency

Rome to Karlsruhe bus times

Buses run once daily between Rome and Karlsruhe. The service departs Rome at 4:35 PM in the afternoon, which arrives into Karlsruhe at 11:10:00. All services run direct with no transfers required, and take on average 18h 35m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Departing Wednesday, November 11, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Departing Thursday, November 12, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Departing Friday, November 13, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Departing Saturday, November 14, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Departing Sunday, November 15, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Departing Monday, November 16, 2026

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    Arrives next day

    bus bus 18h 35m • Direct

Frequently asked questions

Want to know about travelling from Rome to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Karlsruhe.ExpandLaunch map view
  • Distance: 1,183.8 km
  • Duration: 18h 35m

What companies run services between Rome, Italy and Karlsruhe, Germany?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Karlsruhe central train station twice daily. Tickets cost €100–160 and the journey takes 18h 35m. Onebus also services this route once a week.

Operators