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Rome to Lastra a Signa buses

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Trip Overview

The average bus between Rome and Lastra a Signa takes 3h 57m and the fastest bus takes 3h 14m. The bus service runs several times per day from Rome to Lastra a Signa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 57m
Duration
301 km
Distance
€20
Average price
Twice daily
Frequency

Rome to Lastra a Signa bus times

Buses run twice daily between Rome and Lastra a Signa. The earliest departure is at 12:20 AM at night, and the last departure from Rome is at 7:30 AM which arrives into Lastra a Signa at 12:11 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 3h 57m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    FlixBusAutolinee Toscane3h 41m • 1 change

Departing Wednesday, November 4, 2026

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    FlixBusAutolinee Toscane4h 24m • 1 change
  •  → 

    FlixBusAutolinee Toscane3h 41m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    FlixBusAutolinee Toscane4h 24m • 1 change
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    Autoservizi Salemi SrlAutolinee Toscane3h 14m • 1 change
  •  → 

    FlixBusAutolinee Toscane3h 41m • 1 change

Departing Friday, November 6, 2026

  •  → 

    FlixBusAutolinee Toscane4h 24m • 1 change
  •  → 

    FlixBusAutolinee Toscane3h 41m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    FlixBusAutolinee Toscane4h 24m • 1 change
  •  → 

    FlixBusAutolinee Toscane3h 41m • 1 change

Departing Monday, November 9, 2026

  •  → 

    FlixBusAutolinee Toscane4h 24m • 1 change

Frequently asked questions

Want to know about travelling from Rome to Lastra a Signa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Lastra a Signa.ExpandLaunch map view
  • Distance: 300.8 km
  • Duration: 3h 57m

What companies run services between Rome, Italy and Lastra a Signa, Italy?

Itabus S.p.A. operates a bus from Rome Tiburtina Largo Mazzoni to Florence Villa Constanza Bus Station every 4 hours. Tickets cost €15–27 and the journey takes 3h 50m. Two other operators also service this route.

Operators