The average bus between Rome and Otranto Porto takes 10h 55m and the fastest bus takes 9h 35m. The bus service runs several times per day from Rome to Otranto Porto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rome and Otranto Porto. The earliest departure is at 6:50 AM in the morning, and the last departure from Rome is at 11:45 PM which arrives into Otranto Porto at 11:20 AM. All services require a transfer, and take on average 10h 55m. The schedules shown below are for the next available departures.

11h 15m • 1 change
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9h 35m • 1 change
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11h 35m • 1 change

10h 25m • 1 change

11h 15m • 1 change
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9h 35m • 1 change
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11h 35m • 1 change

10h 25m • 1 change

11h 15m • 1 change
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9h 35m • 1 change
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11h 35m • 1 change

10h 25m • 1 change

11h 15m • 1 change
Arrives next day

9h 35m • 1 change
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11h 35m • 1 change

10h 25m • 1 change

11h 15m • 1 change
Arrives next day

9h 35m • 1 change
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11h 35m • 1 change
Want to know about travelling from Rome to Otranto Porto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Otranto Porto. However, there are services departing from Rome station and arriving at Otranto Porto station via Lecce. The journey, including transfers, takes approximately 10h 55m.
Rome to Otranto Porto bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Otranto Porto bus services, operated by FlixBus, arrive at Otranto - Porto station.
The distance between Rome and Otranto Porto is 539.3 km. The road distance is 666 km.
You can take a bus from Roma, Autostazione Tiburtina to Otranto - Porto via Lecce - City Terminal in around 11h 10m.