Rome2Rio

Rome to Palermo buses

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Trip Overview

The average bus between Rome and Palermo takes 12h 35m and the fastest bus takes 11h 45m. The bus service runs several times per day from Rome to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 35m
Duration
951 km
Distance
€85
Average price
Twice daily
Frequency

Rome to Palermo bus times

Buses run twice daily between Rome and Palermo. The earliest departure is at 1:20 AM at night, and the last departure from Rome is at 8:00 PM which arrives into Palermo at 7:45 AM. All services run direct with no transfers required, and take on average 12h 35m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    bus bus 11h 45m • Direct

Departing Tuesday, November 10, 2026

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    bus bus 13h 55m • Direct
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    Arrives next day

    bus bus 11h 45m • Direct

Departing Wednesday, November 11, 2026

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    bus bus 13h 55m • Direct
  •  → 

    Arrives next day

    bus bus 11h 45m • Direct

Departing Thursday, November 12, 2026

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    Arrives next day

    bus bus 11h 45m • Direct

Departing Friday, November 13, 2026

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    Arrives next day

    bus bus 11h 45m • Direct

Departing Saturday, November 14, 2026

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    bus bus 13h 55m • Direct
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    Arrives next day

    bus bus 11h 45m • Direct

Departing Sunday, November 15, 2026

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    bus bus 13h 55m • Direct
  •  → 

    Arrives next day

    bus bus 11h 45m • Direct

Frequently asked questions

Want to know about travelling from Rome to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Palermo.ExpandLaunch map view
  • Distance: 951.1 km
  • Duration: 12h 35m

What companies run services between Rome, Italy and Palermo, Italy?

Autoservizi Salemi Srl operates a bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus twice daily. Tickets cost €35–55 and the journey takes 11h 45m. FlixBus also services this route 5 times a week.

Operators