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Rome to Piazza del Duomo buses

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Trip Overview

The average bus between Rome and Piazza del Duomo takes 10h 34m and the fastest bus takes 8h 8m. The bus service runs several times per day from Rome to Piazza del Duomo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 34m
Duration
597 km
Distance
€63
Average price
Twice daily
Frequency

Rome to Piazza del Duomo bus times

Buses run twice daily between Rome and Piazza del Duomo. The earliest departure is at 10:40 AM in the morning, and the last departure from Rome is at 9:45 PM which arrives into Piazza del Duomo at 5:53 AM. All services require a transfer at Milano, San Donato M3 and take an average of 10h 34m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    FlixBusATM14h 22m • 1 change
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    Arrives next day

    FlixBusATM8h 8m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    FlixBusATM14h 22m • 1 change
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    Arrives next day

    FlixBusATM8h 8m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    FlixBusATM10h 17m • 1 change
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    Arrives next day

    FlixBusATM8h 8m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    FlixBusATM14h 22m • 1 change
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    Arrives next day

    FlixBusATM8h 8m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    FlixBusATM10h 17m • 1 change
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    Arrives next day

    FlixBusATM8h 8m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    FlixBusATM14h 22m • 1 change
  •  → 

    Arrives next day

    FlixBusATM8h 8m • 1 change

Frequently asked questions

Want to know about travelling from Rome to Piazza del Duomo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Piazza del Duomo.ExpandLaunch map view
  • Distance: 597.4 km
  • Duration: 10h 34m

What companies run services between Rome, Italy and Piazza del Duomo, Lombardy, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Milano, San Donato M3 every 3 hours. Tickets cost €50–80 and the journey takes 7h 30m.

Operators