Rome2Rio

Rome to Prague hl.n. buses

Find Transport to Prague hl.n.

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Trip Overview

The bus between Rome and Prague hl.n. takes 20h 10m. The bus runs, on average, 3 times per week from Rome to Prague hl.n.. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 10m
Duration
1,425 km
Distance
Kč 2,700
Average price
3 times a week
Frequency

Rome to Prague hl.n. bus times

Buses run 3 times a week between Rome and Prague hl.n.. The service departs Rome at 1:00 PM in the afternoon, which arrives into Prague hl.n. at 09:10:00. All services run direct with no transfers required, and take on average 20h 10m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    bus bus 20h 10m • Direct

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    bus bus 20h 10m • Direct

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    bus bus 20h 10m • Direct

Frequently asked questions

Want to know about travelling from Rome to Prague hl.n.? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Prague hl.n..ExpandLaunch map view
  • Distance: 1,425.4 km
  • Duration: 20h 10m

What companies run services between Rome, Italy and Prague hl.n., Czechia?

RegioJet operates a bus from Rome Tiburtina Bus Station to Prague Florenc Central Bus Station 4 times a week. Tickets cost Kč 2,200–3,600 and the journey takes 20h 10m.

Operators