The average bus between Rome and Provincia di Siena (Region) takes 4h 56m and the fastest bus takes 3h 30m. The bus service runs several times per day from Rome to Provincia di Siena (Region). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Rome and Provincia di Siena (Region). The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 9:45 PM which arrives into Provincia di Siena (Region) at 7:07 AM. All services require a transfer at Siena and take an average of 4h 56m. The schedules shown below are for the next available departures.

3h 57m • 1 change

5h 2m • 1 change

3h 52m • 1 change
Arrives next day

9h 22m • 1 change

3h 32m • 1 change

4h 51m • 1 change

3h 30m • 1 change

3h 57m • 1 change

3h 32m • 1 change

4h 51m • 1 change

3h 30m • 1 change

3h 57m • 1 change

6h 23m • 1 change

3h 44m • 1 change

5h 2m • 1 change

3h 52m • 1 change

3h 32m • 1 change

4h 51m • 1 change

3h 30m • 1 change

3h 57m • 1 change

4h 47m • 1 change

3h 30m • 1 change

3h 57m • 1 change

3h 52m • 1 change
Want to know about travelling from Rome to Provincia di Siena (Region)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Provincia di Siena (Region). However, there are services departing from Rome station and arriving at Provincia di Siena (Region) station via Siena. The journey, including transfers, takes approximately 4h 56m.
Rome to Provincia di Siena (Region) bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Provincia di Siena (Region) bus services, operated by FlixBus, arrive at Siena station.
The distance between Rome and Provincia di Siena (Region) is 171.8 km. The road distance is 248 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Siena every 3 hours. Tickets cost €18–30 and the journey takes 2h 39m. AutoLinee Moretti also services this route 3 times a week.