The average bus between Rome and San Gusmè takes 5h 52m and the fastest bus takes 4h 9m. The bus service runs several times per day from Rome to San Gusmè. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Rome and San Gusmè. The earliest departure is at 7:45 AM in the morning, and the last departure from Rome is at 9:45 PM which arrives into San Gusmè at 8:24 AM. All services require a transfer at Siena and take an average of 5h 52m. The schedules shown below are for the next available departures.

4h 9m • 1 change

5h 13m • 1 change

4h 18m • 1 change

4h 15m • 1 change

4h 9m • 1 change

5h 13m • 1 change

4h 18m • 1 change

4h 15m • 1 change
Want to know about travelling from Rome to San Gusmè? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to San Gusmè. However, there are services departing from Rome station and arriving at San Gusmè station via Siena. The journey, including transfers, takes approximately 5h 52m.
Rome to San Gusmè bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to San Gusmè bus services, operated by FlixBus, arrive at S.Gusme' station.
The distance between Rome and San Gusmè is 184.5 km. The road distance is 259 km.
You can take a bus from Roma, Autostazione Tiburtina to S.Gusme' via Siena and Siena Autostazione in around 4h 27m.