Rome2Rio

Rome to San Sano buses

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Trip Overview

The average bus between Rome and San Sano takes 6h 2m and the fastest bus takes 3h 33m. The bus service runs several times per day from Rome to San Sano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 2m
Duration
256 km
Distance
€23
Average price
Twice daily
Frequency

Rome to San Sano bus times

Buses run twice daily between Rome and San Sano. The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 9:45 PM which arrives into San Sano at 1:35 PM. All services require a transfer at Siena and take an average of 6h 2m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    FlixBusAutolinee Toscane4h 14m • 1 change

Departing Friday, November 6, 2026

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    FlixBusAutolinee Toscane5h 5m • 1 change
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    FlixBusAutolinee Toscane4h 14m • 1 change

Departing Saturday, November 7, 2026

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    FlixBusAutolinee Toscane5h 5m • 1 change
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    FlixBusAutolinee Toscane3h 33m • 1 change

Departing Monday, November 9, 2026

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    FlixBusAutolinee Toscane5h 5m • 1 change
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    FlixBusAutolinee Toscane5h 44m • 1 change

Departing Tuesday, November 10, 2026

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    FlixBusAutolinee Toscane7h 5m • 1 change
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    FlixBusAutolinee Toscane5h 44m • 1 change
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    Arrives next day

    FlixBusAutolinee Toscane15h 50m • 1 change

Departing Wednesday, November 11, 2026

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    FlixBusAutolinee Toscane5h 44m • 1 change

Frequently asked questions

Want to know about travelling from Rome to San Sano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to San Sano.ExpandLaunch map view
  • Distance: 255.8 km
  • Duration: 6h 2m

What companies run services between Rome, Italy and San Sano, Italy?

You can take a bus from Roma, Autostazione Tiburtina to S.Sano via Siena and Siena Autostazione in around 4h 20m.

Operators