The average bus between Rome and Sant'Anastasia takes 3h 42m and the fastest bus takes 3h 8m. The bus service runs several times per day from Rome to Sant'Anastasia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Rome and Sant'Anastasia. The earliest departure is at 10:40 AM in the morning, and the last departure from Rome is at 7:30 PM which arrives into Sant'Anastasia at 10:41 PM. All services require a transfer, and take on average 3h 42m. The schedules shown below are for the next available departures.

4h 8m • 1 change

3h 23m • 1 change

3h 43m • 1 change

4h 13m • 1 change
Want to know about travelling from Rome to Sant'Anastasia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Sant'Anastasia. However, there are services departing from Rome station and arriving at Sant'Anastasia station via Napoli P.zza Garibaldi. The journey, including transfers, takes approximately 3h 42m.
Rome to Sant'Anastasia bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Sant'Anastasia bus services, operated by FlixBus, arrive at Napoli P.zza Garibaldi station.
The distance between Rome and Sant'Anastasia is 195.8 km. The road distance is 234 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Napoli P.zza Garibaldi hourly. Tickets cost €19–35 and the journey takes 2h 35m.