Rome2Rio

Rome to Santander buses

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Trip Overview

The bus between Rome and Santander takes 36h 25m. The bus runs, on average, 2 times per week from Rome to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 25m
Duration
1,882 km
Distance
€200
Average price
Twice a week
Frequency

Rome to Santander bus times

Buses run twice a week between Rome and Santander. The service departs Rome at 7:35 PM in the evening, which arrives into Santander at 08:00:00. All services require a transfer at Toulon and take an average of 36h 25m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusALSA36h 25m • 2 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusALSA36h 25m • 2 changes

Frequently asked questions

Want to know about travelling from Rome to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Santander.ExpandLaunch map view
  • Distance: 1,881.9 km
  • Duration: 36h 25m

What companies run services between Rome, Italy and Santander, Spain?

You can take a bus from Roma, Autostazione Tiburtina to Estación de autobuses de Santander via Toulon, Bilbao, and Bilbao Intermodal in around 28h 49m.

Operators