The average bus between Rome and Santeramo in Colle takes 7h 35m and the fastest bus takes 7h 5m. The bus service runs several times per day from Rome to Santeramo in Colle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Rome and Santeramo in Colle. The earliest departure is at 9:15 AM in the morning, and the last departure from Rome is at 11:45 PM which arrives into Santeramo in Colle at 7:35 AM. All services require a transfer at Bari and take an average of 7h 35m. The schedules shown below are for the next available departures.

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Want to know about travelling from Rome to Santeramo in Colle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Santeramo in Colle. However, there are services departing from Rome station and arriving at Santeramo in Colle station via Bari. The journey, including transfers, takes approximately 7h 35m.
Rome to Santeramo in Colle bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Santeramo in Colle bus services, operated by FlixBus, arrive at Santeramo in Colle station.
The distance between Rome and Santeramo in Colle is 376.2 km. The road distance is 469 km.
You can take a bus from Roma, Autostazione Tiburtina to Santeramo in Colle via Bari and Bari via Capruzzi in around 7h 45m.