The average bus between Rome and Serrano takes 10h 57m and the fastest bus takes 9h 30m. The bus service runs several times per day from Rome to Serrano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Rome and Serrano. The earliest departure is at 9:00 AM in the morning, and the last departure from Rome is at 11:45 PM which arrives into Serrano at 12:35 PM. All services require a transfer, and take on average 10h 57m. The schedules shown below are for the next available departures.

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9h 30m • 1 change
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10h • 1 change
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9h 30m • 1 change
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10h 50m • 1 change

10h • 1 change
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10h • 1 change
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9h 30m • 1 change
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12h 50m • 1 change
Want to know about travelling from Rome to Serrano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Serrano. However, there are services departing from Rome station and arriving at Serrano station via Lecce. The journey, including transfers, takes approximately 10h 57m.
Rome to Serrano bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Serrano bus services, operated by FlixBus, arrive at Lecce station.
The distance between Rome and Serrano is 526.4 km. The road distance is 651 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Lecce every 4 hours. Tickets cost €50–85 and the journey takes 8h 20m.