Rome2Rio

Rome to Southampton buses

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Trip Overview

The average bus between Rome and Southampton takes 42h 44m and the fastest bus takes 42h 35m. The bus runs, on average, 5 times per week from Rome to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 44m
Duration
1,799 mi
Distance
£212
Average price
5 times a week
Frequency

Rome to Southampton bus times

Buses run 5 times a week between Rome and Southampton. The service departs Rome at 3:20 PM in the afternoon, which arrives into Southampton at 09:10:00. All services require a transfer at Bruxelles - Rue du Progrès and take an average of 42h 44m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    BlaBlaCar BusBlaBlaCar BusNational Express42h 50m • 2 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    BlaBlaCar BusBlaBlaCar BusNational Express42h 50m • 2 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    BlaBlaCar BusBlaBlaCar BusNational Express42h 50m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    BlaBlaCar BusBlaBlaCar BusNational Express42h 35m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    BlaBlaCar BusBlaBlaCar BusNational Express42h 35m • 2 changes

Frequently asked questions

Want to know about travelling from Rome to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Rome to Southampton.ExpandLaunch map view
  • Distance: 1,799.3 mi
  • Duration: 42h 44m

What companies run services between Rome, Italy and Southampton, England?

You can take a bus from Roma Prenestina A1 to Coach Station via Bruxelles - Rue du Progrès, Rogier, Suede, Brussels Midi / Brussels South West, London Victoria Green Line Station, and London Victoria in around 30h 50m.

Operators