The average bus between Rome and Syracuse takes 11h 41m and the fastest bus takes 11h 29m. The bus runs, on average, 6 times per week from Rome to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Rome and Syracuse. The earliest departure is at 8:00 PM in the evening, and the last departure from Rome is at 8:00 PM which arrives into Syracuse at 7:29 AM. All services require a transfer at Catania Via D'Amico and take an average of 11h 41m. The schedules shown below are for the next available departures.
Want to know about travelling from Rome to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Syracuse. However, there are services departing from Rome station and arriving at Syracuse station via Catania Via D'Amico. The journey, including transfers, takes approximately 11h 41m.
Rome to Syracuse bus services, operated by Autoservizi Salemi Srl, depart from Roma, Autostazione Tiburtina station.
Rome to Syracuse bus services, operated by Autoservizi Salemi Srl, arrive at Siracusa - Von Platen station.
Book your Rome to Syracuse bus tickets online with Autoservizi Salemi Srl and Interbus.
The distance between Rome and Syracuse is 587.4 km. The road distance is 868 km.
You can take a bus from Roma, Autostazione Tiburtina to Siracusa - Von Platen via Catania Via D'Amico and Catania Via Archimede in around 11h 36m.
