The average bus between Rotherhithe and Slough takes 2h 21m and the fastest bus takes 1h 50m. There is a bus service every few hours from Rotherhithe to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Rotherhithe and Slough. The earliest departure is at 5:55 AM in the morning, and the last departure from Rotherhithe is at 10:41 PM which arrives into Slough at 12:32 AM. All services require a transfer, and take on average 2h 21m. The schedules shown below are for the next available departures.

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2h 20m • 1 changeWant to know about travelling from Rotherhithe to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rotherhithe to Slough. However, there are services departing from Smith Close station and arriving at Wellington Street Stop H station via Victoria Station. The journey, including transfers, takes approximately 2h 21m.
Rotherhithe to Slough bus services, operated by Transport UK London Bus, depart from Smith Close station.
Rotherhithe to Slough bus services, operated by Reading Buses, arrive at Wellington Street Stop H station.
The distance between Rotherhithe and Slough is 38.2 km. The road distance is 42 km.
You can take a bus from Smith Close to Wellington Street Stop H via Victoria Station in around 2h 32m.