The average bus between Ruzyně and Karlovy Vary takes 3h 3m and the fastest bus takes 2h 30m. The bus service runs several times per day from Ruzyně to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Ruzyně and Karlovy Vary. The earliest departure is at 7:03 AM in the morning, and the last departure from Ruzyně is at 11:34 PM which arrives into Karlovy Vary at 7:26 AM. All services require a transfer at Václav Havel Airport T1 and take an average of 3h 3m. The schedules shown below are for the next available departures.

2h 38m • 1 change

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2h 38m • 1 change

2h 43m • 1 change

2h 35m • 1 change

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2h 43m • 1 change

2h 42m • 1 change

2h 35m • 1 change

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2h 38m • 1 change

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2h 38m • 1 change
Want to know about travelling from Ruzyně to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ruzyně to Karlovy Vary. However, there are services departing from Ruzyně station and arriving at Karlovy Vary station via Karlovy Vary Trznice Bus Station station. The journey, including transfers, takes approximately 3h 3m.
Ruzyně to Karlovy Vary bus services, operated by Pražská integrovaná doprava, depart from Prague Airport Terminal 1/2 station.
Ruzyně to Karlovy Vary bus services, operated by Pražská integrovaná doprava, arrive at Karlovy Vary Trznice Bus Station.
The distance between Ruzyně and Karlovy Vary is 103.2 km. The road distance is 122 km.
RegioJet operates a bus from Prague Airport Terminal 1/2 to Karlovy Vary Trznice Bus Station hourly. Tickets cost Kč 220–310 and the journey takes 1h 40m. FlixBus also services this route once daily.