The average bus between Sète and Gare de Lyon-Perrache takes 5h 58m and the fastest bus takes 5h 15m. The bus service runs several times per day from Sète to Gare de Lyon-Perrache. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Sète and Gare de Lyon-Perrache. The earliest departure is at 7:05 AM in the morning, and the last departure from Sète is at 7:30 PM which arrives into Gare de Lyon-Perrache at 1:10 AM. All services require a transfer at Montpellier - Sabines Tw2 and take an average of 5h 58m. The schedules shown below are for the next available departures.

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Want to know about travelling from Sète to Gare de Lyon-Perrache? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sète to Gare de Lyon-Perrache. However, there are services departing from Sète station and arriving at Gare de Lyon-Perrache station via Montpellier - Sabines Tw2. The journey, including transfers, takes approximately 5h 58m.
Sète to Gare de Lyon-Perrache bus services, operated by Hérault - liO Occitanie, depart from Sete - Noel Guignon station.
Sète to Gare de Lyon-Perrache bus services, operated by Hérault - liO Occitanie, arrive at Lyon - Gerland Bus Station.
The distance between Sète and Gare de Lyon-Perrache is 273.5 km. The road distance is 334 km.
You can take a bus from Sete - Noel Guignon to Lyon - Gerland Bus Station via Montpellier - Sabines Tw2 and Montpellier - Sabines Bus Station in around 4h 51m.