The average bus between Sérres and Larissa takes 4h 1m and the fastest bus takes 4h. The bus service runs several times per day from Sérres to Larissa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Sérres and Larissa. The earliest departure is at 6:00 AM in the morning, and the last departure from Sérres is at 8:30 PM which arrives into Larissa at 12:45 AM. All services require a transfer, and take on average 4h 1m. The schedules shown below are for the next available departures.

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Want to know about travelling from Sérres to Larissa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sérres to Larissa. However, there are services departing from Sérres station and arriving at Larissa station via Thessaloniki Macedonia KTEL Bus Station station. The journey, including transfers, takes approximately 4h 1m.
Sérres to Larissa bus services, operated by KTEL Serron, depart from Serres station.
Sérres to Larissa bus services, operated by KTEL Serron, arrive at Larissa station.
The distance between Sérres and Larissa is 187.3 km. The road distance is 230 km.
You can take a bus from Serres to Larissa via Thessaloniki Macedonia KTEL Bus Station in around 4h 45m.