The average bus between Sérres and Tríkala takes 4h 15m and the fastest bus takes 4h. The bus service runs several times per day from Sérres to Tríkala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Sérres and Tríkala. The earliest departure is at 7:30 AM in the morning, and the last departure from Sérres is at 6:30 PM which arrives into Tríkala at 11:00 PM. All services require a transfer, and take on average 4h 15m. The schedules shown below are for the next available departures.

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Want to know about travelling from Sérres to Tríkala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sérres to Tríkala. However, there are services departing from Sérres station and arriving at Tríkala station via Thessaloniki Macedonia KTEL Bus Station station. The journey, including transfers, takes approximately 4h 15m.
Sérres to Tríkala bus services, operated by KTEL Serron, depart from Serres station.
Sérres to Tríkala bus services, operated by KTEL Serron, arrive at Trikala station.
The distance between Sérres and Tríkala is 227.4 km. The road distance is 291 km.
You can take a bus from Serres to Trikala via Thessaloniki Macedonia KTEL Bus Station in around 4h 45m.