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Saco to Hyannis buses

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Trip Overview

The average bus between Saco and Hyannis takes 7h 59m and the fastest bus takes 6h 18m. The bus service runs several times per day from Saco to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 59m
Duration
205 mi
Distance
$63
Average price
5 times a day
Frequency

Line 60 bus, bus

best
  1. Take the bus from Dyer Library to Portland Public Librarybus bus 60
  2. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
  3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
6h 23m
$52–86

Saco to Hyannis bus times

Buses run 5 times a day between Saco and Hyannis. The earliest departure is at 6:17 AM in the morning, and the last departure from Saco is at 7:01 PM which arrives into Hyannis at 8:15 AM. All services require a transfer at Portland Public Library and take an average of 7h 59m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

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    Arrives next day

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton13h 14m • 3 changes

Departing Sunday, October 11, 2026

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton7h 58m • 3 changes

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusConcord Coach LinesPlymouth & Brockton7h 28m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusConcord Coach LinesPlymouth & Brockton7h 43m • 3 changes
  • Show more

Departing Monday, October 12, 2026

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 28m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 43m • 3 changes
  • Show more

Departing Tuesday, October 13, 2026

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 28m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 43m • 3 changes
  • Show more

Departing Wednesday, October 14, 2026

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 28m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 43m • 3 changes
  • Show more

Departing Thursday, October 15, 2026

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    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 28m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 58m • 3 changes

  •  → 

    Biddeford Saco Old Orchard Beach TransitGreater Portland Metro BusAmtrak ThruwayPlymouth & Brockton6h 43m • 3 changes
  • Show more

Frequently asked questions

Want to know about travelling from Saco to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Saco to Hyannis.ExpandLaunch map view
  • Distance: 205 mi
  • Duration: 7h 59m

What companies run services between Saco, ME, USA and Hyannis, MA, USA?

You can take a bus from Dyer Library to Hyannis Transportation Center via Portland Public Library, Portland, ME, Boston, MA - South Station, and Boston South Buses in around 6h 23m.

Operators